ECMOPharmNet
Members
Co-Chairs
Diana Morales Castro
Adult Critical Care, Medico-Surgical Intensive Care Unit, Toronto General Hospital, University of Toronto, Canada.
Dr. Diana Morales Castro is an Anesthetist and Critical Care Specialist from Costa Rica. She works an intensivist at Toronto General Hospital in Canada and Hospital Calderon Guardia in Costa Rica. Her clinical expertise lies in therapeutic monitoring, including pharmacology and echocardiography, for ECMO populations. Dr. Morales Castro completed her Master’s in Pharmaceutical Sciences at the University of Toronto in 2024. Her research interests include sedative pharmacokinetics and pharmacodynamics in patients with acute respiratory distress syndrome, including those supported with ECMO. She also works to improve ECMO delivery in resource-limited settings and bridge the care gap between developed and developing ECMO programs.
Amy Dzierba
Clinical Pharmacy Manager, Adult Critical Care, New York-Presbyterian Hospital, Columbia University, Irving Medical Center, USA.
Dr. Amy Dzierba is a clinical pharmacist in the Medical ICU at New York-Presbyterian Hospital, Columbia University Irving Medical Center. She completed her undergraduate work and Doctor of Pharmacy degree at Midwestern University School of Pharmacy. Thereafter, Dr. Dzierba completed her PGY1 pharmacy residency at Grady Health System followed by a Post-Graduate Year 2 pharmacy residency in critical care at the University of Washington / Harborview Medical Center. Her research interests include sedation/analgesia/delirium in mechanically ventilated patients, pharmacotherapy for the management of ARDS, pharmacokinetic changes in critically ill patients receiving extracorporeal membrane oxygen support, and treatment of patients with pulmonary hypertension.
Kiran Shekar
Adult Intensive Care Services, The Prince Charles Hospital, University of Queensland, Australia.
Dr. Kiran Shekar is a Senior Intensive Care Specialist and Director of Research at the Prince Charles Hospital, Brisbane, Queensland, Australia. He holds academic appointments as Adjunct Professor at Queensland University of Technology and Associate Professor at University of Queensland. Shekar is passionate about addressing the global variability in intensive care and extracorporeal life support (ECLS) outcomes through innovation, research, and education. His research interests include pathophysiology of cardiorespiratory failure, ECLS and mechanical circulatory support. His PhD work,” The ECMO PK Project” resulted in an advanced understanding of altered PK/PD on ECMO and provided doing guidance for commonly used antimicrobial and sedative drugs.
Members
Haifa Lyster
Royal Brompton and Harefield Hospitals, Guy and St Thomas NHS Foundation, UK.
Dr. Lyster is a Fellow of the Royal Pharmaceutical Society and its’ Faculty. She is the consultant pharmacist in Cardiothoracic Transplantation and Mechanical Circulatory Support at Royal Brompton & Harefield Hospitals, managing the pharmaceutical care of VAD/ECMO and heart and lung transplant patients. Dr Lyster is on the board of Directors of the International Society of Heart & Lung Transplantation (ISHLT), having held several leadership roles within the society. She co-founded and is the Chair of Solid Organ Transplant Pharmacy Association. She recently completed a research doctorate developing Pharmacokinetic models of antifungal agents in critically ill patients with ECMO. Her research interests include personalization of dosing in special populations e.g. critically ill patients with or without ECMO, RRT.
Benjamin Hohlfelder
Clinical Specialist Cardiothoracic Intensive Care Unit, Cleveland Clinic, USA.
Ben Hohlfelder is a CVICU Pharmacy Clinical Specialist who has been with Cleveland Clinic since 2016. He previously worked at Brigham and Women’s Hospital (Boston, MA) where he completed his PGY-1 and PGY-2 Pharmacy Residency in Critical Care. Within ECMOPharm, his primary areas of interest are management of pain, agitation and delirium, anticoagulation management strategies, and treatment strategies for refractory vasoplegic shock in patients requiring mechanical circulatory support.
Daniel Herr
Surgical Critical Care, Medical University of South Carolina, USA.
Dr. Herr is an intensivist with 38 years’ experience in the practice of adult critical care. He now is employed at the Medical University of South Carolina, working in the CS-ICU. He has experience in trauma, neuro, medical, surgical, and cardiovascular critical care. For the last 20 years his emphasis has practiced cardio-thoracic critical care. He served as Chief of Critical Care at the University of Maryland and as the Director of the cardiac surgery, heart-lung transplant ICU and director of University of Maryland ECMO service. He has over 30 years of experience working with ECLS devices. He has served on several Data Safety Monitoring Boards, as chair of MedStar IRB and provides consultative services to pharmaceutical companies and ECMO programs. His ongoing goal is continuing to assist others to find better, safer ways to provide ECLS to patients.
Rawan Alraish
Anesthesia Department, Charite University Hospital, Berlin, Germany.
Rawan Alraish born and raised from Kuwait moved to berlin, Germany to complete her medical studies at The Charité-University Hospital in 2020. During her undergraduate years, she embarked on a doctoral project concerning the appropriate dosage of antibiotics for critically ill patients starting in 2016. Her subsequent research concentrated on the pharmacokinetics of antibiotics and antifungals among adult patients receiving extracorporeal life support at Al-Amiri Hospital in Kuwait. Presently, she is pursuing a postgraduate residency program in Anesthesia at Charité University Hospital, Berlin, Germany. As a member of the ECMOPharm Rawan is particularly interested in the intersection of pharmacology and ECMO, with a focus on optimizing drug dosing and management for patients on extracorporeal life support.
Andrés Ferre Contreras
Coordinator Critical Care Patient Center, Clínica Las Condes, Chile.
As head of teaching and research and also, coordinator of the Critical Patient Center at Clínica Las Condes, Dr. Ferre focus is on promoting academic excellence and innovation in the care of critically ill patients. My interests in ECMO and pharmacology lies in exploring new pharmacological therapies and, above all, optimizing treatment in these patients to improve results.
Gianluca Paternoster
Department of Cardiac Resuscitation and Intensive Care, San Carlo Hospital, Potenza, Italy.
Dr. Paternoster is a cardiothoracic and vascular anesthesiologist and intensivist at the San Carlo University hospital in Potenza Italy. He is the ECMO and DCD program manager with research interest in the ECMO sector, with particular attention to awake ECMO techniques. Author of papers and book chapters in the field of ECMO strategies and coagulation management in ECMO.
Jordi Riera del Brio
Critical Care Department, University Hospital Vall d’Hebron, Spain.
Dr Riera is an adult critical care physician at the Vall d’Hebron University Hospital in Barcelona, Spain. He is the adult ECMO Program Director at this institution and tutor of ICU residents. He is part of the EuroELSO Steering Committee and ELSO Research Committee & Scientific Oversight Committee. PhD (cum laude & extraordinary award at Universitat Autònoma de Barcelona) and PI of several investigations on ECMO, lung transplant and respiratory infectious diseases (ORCID: 0000-0002-1738-4448). This includes investigations on PK/PD of antibiotics in patients with ECLS and also studies on nebulized antibiotics in the critically ill patient receiving mechanical ventilation.
Luigi Miella
University of Basilicata, Italy.
Prof. Luigi Milella achieved his Ph.D. in Biology and Biotechnology at the University of Basilicata. Now, he is an Associate Professor in Pharmaceutical Biology at the Department of Science and Coordinator of the MsC of Pharmacy. He carries out research focused on the chemical structure, bioavailability and biological activity of small molecules from different sources, by using advanced chromatographic methods, in vitro cell-based and in silico studies. He also conducts research in the field of gender medicine to define differences in drug efficacy.
Pauline Dureau
Department of Anesthesiology and Critical Care Medicine, Cardiology Institute, Sorbonne University, France.
Dr. Pauline Dureau is an anesthesiologist and critical care specialist at the Pitié-Salpêtrière Hospital, affiliated with Sorbonne University in Paris. In addition to her medical degree, she obtained a Master of Science and a postgraduate diploma in pharmacology. Dr. Dureau Dr. Dureau has a specialization in cardiac anesthesia and ECMO, with a focus on organ transplantation management. She is actively involved in clinical research and teaching, particularly in ECMO applications, pathophysiology of respiratory failure, and pharmacology. She is leading local studies PK/PD of antibiotics in patients with ECLS and also studies on nebulized antibiotics in the critically ill. As a member of the ECMOPharm, she is particularly interested in the potential for pharmacology to enhance the care of patients on extracorporeal life support.
M. Hafiz Abdul-Aziz
Early Career Research Fellow, University of Queensland Centre for Clinical Research, Australia.
Dr Hafiz Abdul–Aziz is an Early Career Research Fellow and a Clinical Research Pharmacist at The University of Queensland Centre for Clinical Research (UQCCR) at The University of Queensland, Australia. He is a Clinical Research Associate and Clinical Trial Monitor at The George Institute for Global Health, Australia. Dr Abdul–Aziz received his Bachelor of Pharmacy (Hons) and Master of Clinical Pharmacy degrees from Malaysia, prior to completing his PhD at The University of Queensland in 2016. His current research program seeks to define novel and innovative methods to optimize antimicrobial dosing/delivery to improve patient outcomes in the ICU, including those receiving ECMO. Dr Abdul–Aziz is a Fellow of the International Society of Antimicrobial Chemotherapy (ISAC) and the current Chair of the Infections in the ICU and Sepsis Working Group of International Society of Antimicrobial Chemotherapy (ISAC).
Afrah Alkazemi
Department of Pharmacy Practice, College of Pharmacy, Kuwait University, Kuwait.
Dr. Alkazemi works as an Assistant Professor at Kuwait University’s College of Pharmacy. She holds a Bachelor of Pharmacy from Kuwait University (2008), an MSc in Clinical Pharmacy from University College London (2014), and a PharmD from MCPHS University, Boston, USA (2018). She completed a PGY1 Pharmacy Residency at BIDMC Hospital, Boston, USA (2019). Dr. Alkazemi undertook two clinical research pharmacy fellowships at Brigham and Women’s Hospital, Boston, specializing in Quality and Safety (2020) and Critical Care (2021).
Julian Arias Ortiz
Cardiothoracic and Transplant Unit, Hospital Calderon Guardia, Costa Rica.
Dr. Arias Ortiz is a Senior Attending Critical Care Physician at Calderon Guardia Hospital, a Public Social Security, University Affiliated Hospital, and a high complexity center with Cardiac surgery, heart, lung, liver transplant programs and ECMO/VAD capacity. His background formation is in Internal Medicine and Critical Care, with expertise in cardiac surgery, heart/lung and liver transplant, ECMO support and ventricular assist devices. He is working with the University of Costa Rica to develop antimicrobial TDM to optimize dosage regimens in the ICU and ECMO patients.
Jason Roberts
Director University of Queensland Centre for Clinical Research, Australia.
Professor Jason Roberts is the Director of the University of Queensland Centre for Clinical Research (UQCCR) and an Australian National Health and Medical Research Council Leadership Fellow at The University of Queensland. He is a Clinical Pharmacist at Royal Brisbane and Women’s Hospital where he is also the Interim Director of the Herston Infectious Diseases Institute (HeIDI). He leads the Centre of Research Excellence RESPOND which aims to develop optimised antibiotic dosing regimens to improve patient outcomes and minimise the emergence of antibiotic-resistant superbugs. His work with Dr. Shekar resulted in the largest PK studies in ECMO antimicrobials.
Mark Alm
Cardiovascular perfusion, Toronto General Hospital, Canada.
Mark Alm is a Cardiovascular Perfusionist at University Health Network and MSc student at the Medical University of South Carolina. He previously worked as an ICU RN caring for ECLS patients. His interests include: standardization of criteria for extracorporeal circuit dysfunction, clinical applications for ECMO exhaust gas analysis, and the impact of extracorporeal circulation systems on pharmacokinetics and its relevance to clinical decision-making.
Marc-Alexandre Duceppe
Department of Pharmacy, McGill University, Canada.
Marc-Alexandre Duceppe is a clinical pharmacist in critical care at the McGill University Health Centre in Montreal. After completing a Doctorate in Pharmacy and a Master’s degree in advanced pharmacotherapy at Université de Montréal in 2013, he started contributing in research related to geriatrics and critical care. He is interested in the clinical management of sedation and analgesia in the intensive care. He published and contributed to studies in regards to the weaning and withdrawal from these agents. His recent research contributions revolved around therapeutic drug monitoring of antimicrobials in the ECMO population.
Federico Carini
Intensive Care Unit, Hospital Italiano, Argentina.
Dr. Carini is a critical care physician, original from Argentina, currently doing a clinical and research fellow at the University of Toronto (Ontario, Canada). He finished his residence in critical care in 2013, and then worked for 10+ years as a staff with a focus on implementation on delirium and sedation best practices in the ICU. He also completed a MSc in clinical effectiveness, and a specialization in medical education. His interest in ECMOPharm is related to his commitment to implement best practices in particular related to the ABCDEF bundle. On a side note, he is a sport (triathlon) enthusiast, with more enthusiasm than success.
Alba Pau Parra
Pharmacy Department, Vall d’Hebron University Hospital, Spain.
Alba Pau is a clinical pharmacist in the Intensive Care Unit of the Vall d’Hebron University Hospital in Barcelona, Spain. She has extensive experience in therapeutic monitoring of antimicrobial agents in critically ill patients, playing a key role in the Antimicrobial Stewardship Program. With an emphasis on personalized medicine, her research is focused on clinical PK/PD studies of antimicrobials and pharmacokinetic modeling in patients receiving ECMO support to ensure optimal dosing and better clinical outcomes. As a member of the ECMOPharm, she is especially interested in PK/PD of newer antimicrobials for multidrug-resistant infections.
Claudia Catarinella
Cardiothoracic and Transplant Unit, Hospital Calderon Guardia, Costa Rica.
Dr. Claudia Catarinella is an Internal Medicine and Critical Care Specialist at Hospital Calderón Guardia in Costa Rica. She provides specialized care to critically ill patients, with a particular focus on those requiring extracorporeal membrane oxygenation (ECMO) support and organ transplant. Dr. Catarinella is dedicated to advancing ECMO management and patient outcomes in resource limited settings. Her research interests include differences in pharmacological approaches in resource limited settings and developed countries and optimizing clinical protocols for ECMO patients.
Patrick Wieruszewski
Department of Pharmacy, Department of Anesthesiology, Mayo Clinic, USA
Patrick Wieruszewski is a clinical pharmacist in the cardiothoracic surgery and ECMO program at Mayo Clinic. He received a Bachelor of Science degree in Chemistry and Materials Engineering from the University of Florida and has a background in solid-state physics. Following this he received a Doctor of Pharmacy degree from University of Florida and completed residency training specializing in critical care at Mayo Clinic. He serves as Chairman for clinical pharmacy research in Mayo Clinic Midwest, is board certified in critical care pharmacotherapy, and holds dual academic rank at the Assistant Professor level in the fields of Anesthesiology and Pharmacy in the Mayo Clinic College of Medicine. His research focuses on human circulatory physiology, shock, vasoactive medications, and mechanical life support devices.
Joseph Marcus
Brooke Army Medical Center & Uniformed Services University of Health Sciences, USA
Joseph Marcus is an Assistant Professor of Medicine at the Uniformed Services University of Health Sciences and an infectious diseases physician at Brooke Army Medical Center. His research interests are in the diagnosis and treatment of ECMO-associated infections with particular interest on optimizing antimicrobials to improve outcomes for patients receiving ECMO.
Vivek Kakar
Section Head, Cardiac Critical Care and ECMO, Critical Care Institute, Cleveland Clinic, Abu Dhabi.
Kevin Watt
Division of Clinical Pharmacology, University of Utah, USA.
Marcela Palavecino
Pontificia Universidad Católica de Chile, Chile.
Abdulrahman Al-Fares
Chair Department of Anesthesia Critical Care Medicine and Pain Medicine and Director of Kuwait Extracorporeal Life Support Program, Al-Amiri Hospital, Kuwait.
Stephanie Cha
Department of Anaesthesiology and Critical Care Medicine, John Hopkins University School of Medicine, USA.
ECMOPharm Net
Multidisciplinary Network of Extracorporeal Membrane Oxygenation Experts